ADC类靶点蛋白、裸抗及ADC相关酶的应用与合集

近岸蛋白提供ADC药物开发中所需的靶点蛋白、裸抗、ADC定点偶联酶和ADC linker裂解酶。

靶点蛋白产品特点

哺乳动物细胞表达

3000+靶点蛋白产品，种类齐全

高活性：经过ELISA/BLI验证

高批间一致性

裸抗产品特点

各种靶点的裸抗，种类丰富

纯度高，经过SDS-PAGE验证

活性好，经过ELISA/BLI验证

高批间一致性

部分数据展示

生物活性经ELISA抗体结合验证

Immobilized Human TROP-2-His (Cat#CU64) at 1 μg/ml (100 μl/well) can bind Human TROP-2 Antibody (Sacituzumab, Research Grade) (Cat#NC045). The ED50 of Anti-Human TROP-2 mAb (Sacituzumab, Research Grade) (Cat#NC045) is 4.31 ng/ml.

Immobilized Recombinant Cynomolgus NaPi2b-Flag (Cat#C27X) at 2 μg/ml (100 μl/well) can bind Human NaPi2b Antibody (Upifitamab, Research Grade) (Cat#NC091). The ED50 of Human NaPi2b Antibody (Upifitamab, Research Grade) (Cat#NC091) is 3.61 ng/ml.

Immobilized Human Nectin-4 Antibody (Enfortumab, Research Grade) (Cat#NC280) at 5 μg/ml (100 μl/well) can bind Recombinant Human Nectin-4 (C-6His) (Cat#CJ19). The ED50 of Recombinant Human Nectin-4 (C-6His) (Cat#CJ19) is 140.6 ng/ml.

生物活性经BLI抗体亲和力验证

Loaded Human TROP-2 Antibody (Sacituzumab, Research Grade) (Cat#NC045) on Protein A Biosensor, can bind Human TROP-2-His (Cat#CU64) with an affinity constant of 1.57 nM as determined in BLI assay.

Loaded Human NaPi2b Antibody (Upifitamab, Research Grade) (Cat#NC091) on Pro-A Biosensor, can bind Recombinant Cynomolgus NaPi2b (C-Flag) (Cat#C27X) with an affinity constant of 13.5 nM as determined in BLI assay.